Acceleron  

Publications

  • Publication
    Luspatercept
    Dec 8, 2014
    Luspatercept Increases Hemoglobin and Reduces Transfusion Burden in Patients with Low or Intermediate-1 Risk Myelodysplastic Syndromes: Preliminary Results from a Phase 2 Study. 56th Annual American Society of Hematology Annual Meeting and Exposition; December 8, 2014
    + VIEW FULL Publication
  • Publication
    Luspatercept
    Dec 8, 2014
    Modified ActRIIB-mFc Fusion Protein Mitigates Sickling and Red Cell Pathology in a Murine Model of Sickle Cell Disease. 56th Annual American Society of Hematology Annual Meeting and Exposition; December 8, 2014
    + VIEW FULL Publication
  • Publication
    Sotatercept
    Dec 7, 2014
    An Open-Label, Phase 2, Dose-Finding Study of Sotatercept in Patients With Low- or Intermediate-1-Risk Myelodysplastic Syndromes or Non-Proliferative Chronic Myelomonocytic Leukemia and Anemia Requiring Transfusion. 56th American Society of Hematology Annual Meeting and Exposition; December 7, 2014
    + VIEW FULL Publication
  • Publication
    Luspatercept
    Dec 7, 2014
    Luspatercept Increases Hemoglobin and Decreases Transfusion Burden and Serum Ferritin in Adults with Beta-Thalassemia: Preliminary Results from a Phase 2 Study. 56th American Society of Hematology Annual Meeting and Exposition; December 7, 2014.
    + VIEW FULL Publication
  • Publication
    Sotatercept
    Nov 13, 2014
    Safety and Hemoglobin Effect of the First 28-Day Dose Cycle of Sotatercept 0.7 mg/kg Compared With Lower Doses and Placebo for Correction of Anemia in Hemodialysis Subjects: Interim Analysis. American Society of Nephrology Kidney Week 2014; November 13, 2014
    + VIEW FULL Publication
  • Publication
    Sotatercept
    Nov 13, 2014
    Sotatercept: Results for Bone Mass and Vascular Calcification in Hemodialysis Subjects Treated With Escalating Doses: Interim Analysis of ACE-011-REN-001. American Society of Nephrology Kidney Week 2014; November 13, 2014
    + VIEW FULL Publication
  • Publication
    ACE-083
    Oct 9, 2014
    ACE-083, a Ligand Trap for Members of the TGF-β Superfamily, Increases Muscle Mass Locally in a Mouse Model of Duchenne Muscular Dystrophy . 19th International Congress of the World Muscle Society; October 9, 2014
    + VIEW FULL Publication
  • Publication
    ACE-083
    Jul 7, 2014
    A Modified Cysteine Knot Ligand Trap of the TGF-β Superfamily, ACE-083, Increases Muscle Mass Locally in Mice. 13th International Congress on Neuromuscular Diseases; July 7, 2014
    + VIEW FULL Publication
  • Publication
    Luspatercept
    Jun 19, 2014
    Modified Activin Receptor IIB Ligand Trap Mitigates Ineffective Erythropoiesis and Disease Complications in Murine Beta-Thalassemia. Blood 2014; 123(25):3864-3872
    + VIEW FULL Publication
  • Publication
    Luspatercept
    Jun 13, 2014
    Modified ActRIIB-Fc Fusion Protein (ACE-536) Decreases Irreversible Sickle Cells in a Murine Model of Sickle Cell Disease . European Hematology Associtation 19th Congress; June 13, 2014
    + VIEW FULL Publication
  • Publication
    Sotatercept
    Jun 1, 2014
    Long-term Effects of Sotatercept Compared With Placebo for Correction of Anemia in Hemodialysis Subjects: Interim Analysis of ACE-011-REN-001 Phase 2A Study. 51st ERA-EDTA Congress; May 31-June 1, 2014
    + VIEW FULL Publication
  • Publication
    Dalantercept
    May 30, 2014
    Phase 2 Study of Dalantercept Monotherapy in Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck. American Society of Oncology Annual Meeting; May 30 – June 3, 2014
    + VIEW FULL Publication
  • Publication
    Dalantercept
    May 30, 2014
    A Phase 2 Randomized Study of Dalantercept Plus Axitinib Versus Placebo Plus Axitinib in Advanced Renal Cell Carcinoma: Results from the Part 1 Dose Escalation and Expansion Cohorts. American Society of Oncology Annual Meeting; May 30 – June 3, 2014
    + VIEW FULL Publication
  • Publication
    Luspatercept
    Apr 26, 2014
    A Phase 1 Study of ACE-536, a Regulator of Erythroid Differentiation, in Healthy Volunteers. American Journal of Hematology; published online April 26, 2014
    + VIEW FULL Publication
  • Publication
    Sotatercept
    Apr 23, 2014
    Interim Analysis of ACE-011-REN-001: The First 28 Day Dose Cycle of Low and Medium Starting Doses of Sotatercept Compared to Placebo for Correction of Anemia in Hemodialysis Subjects. Poster #81, National Kidney Foundation (NKF) 2014 Spring Clinical Meeting
    + VIEW FULL Publication
  • Publication
    Luspatercept
    Apr 17, 2014
    Targeting a New Regulator of Erythropoiesis to Alleviate Anemia. Nature Medicine. April 2014; 20(4):334-35
    + VIEW FULL Publication
  • Publication
    Dalantercept
    Apr 8, 2014
    Molecular Pathways: Can Activin-like Kinase Pathway Inhibition Enhance the Limited Efficacy of VEGF Inhibitors? Clinical Cancer Research 2014; published online April 8, 2014
    + VIEW FULL Publication
  • Publication
    Luspatercept
    Mar 25, 2014
    Transforming Growth Factor-β Superfamily Ligand Trap ACE-536 Corrects Anemia by Promoting Late-Stage Erythropoiesis. Nature Medicine 2014; published online March 23, 2014
    + VIEW FULL Publication
  • Publication
    Sotatercept
    Mar 25, 2014
    An Activin IIa Ligand Trap Corrects Ineffective Erythropoiesis in β-Thalassemia. Nature Medicine 2014; published online March 23, 2014
    + VIEW FULL Publication
  • Publication
    Sotatercept
    Mar 21, 2014
    Sotatercept in Patients with Osteolytic Lesions of Multiple Myeloma. British Journal of Haematology 2014; published online March 21, 2014
    + VIEW FULL Publication
  • Publication
    Sotatercept
    Mar 18, 2014
    An Activin Receptor IIA Ligand Trap Promotes Erythropoiesis Resulting in a Rapid Induction of Red Blood Cells and Haemoglobin. British Journal of Haematology 2014; published online March 18, 2014
    + VIEW FULL Publication
  • Publication
    Dalantercept
    Jan 15, 2014
    Safety, Pharmacokinetics, Pharmacodynamics, and Antitumor Activity of Dalantercept, an Activin Receptor-like Kinase 1 Ligand Trap, in Patients with Advanced Cancer. Clin Cancer Research 2014;20:482-89
    + VIEW FULL Publication