Acceleron  

Publications

  • Publication
    Sotatercept
    Dec 1, 2010
    Inhibiting activin-A signaling stimulates bone formation and prevents cancer-induced bone destruction in vivo. J. Bone Miner Res 2010; 25(12): 2633-46
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  • Publication
    Sotatercept
    Oct 1, 2010
    Sotatercept, a soluble activin receptor type 2A IgG-Fc fusion protein for the treatment of anemia and bone loss. Curr Opin Mol Ther 2010;12(5):586-97
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  • Publication
    ACE-031
    Sep 1, 2010
    A Soluble Activin Receptor Type IIB Prevents the Effects of Androgen Deprivation on Body Composition and Bone Health. Endocrinology 2010; 151(9): 4289–4300
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  • Publication
    ACE-031
    Jul 2, 2010
    Characterization of the Ligand Binding Functionality of the Extracellular Domain of Activin Receptor Type IIB. J Biol Chem 2010; 285(27): 21037–21048
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  • Publication
    ACE-031
    May 13, 2010
    Administration of a Soluble Activin Type IIB Receptor Promotes Skeletal Muscle Growth Independent of Fiber Type. J Appl Physiol 2010;109(3):635-42
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  • Publication
    Sotatercept
    Apr 1, 2010
    A soluble activin receptor Type IIA fusion protein (ACE-011) increases bone mass via a dual anabolic-antiresorptive effect in Cynomolgus monkeys. Bone 2010;46(4):1082-8
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  • Publication
    Sotatercept
    Mar 16, 2010
    Activin A promotes multiple myeloma-induced osteolysis and is a promising target for myeloma bone disease. PNAS 2010, 107(11): 5124-5129
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  • Publication
    Dalantercept
    Feb 2, 2010
    ALK1-Fc Inhibits Multiple Mediators of Angiogenesis and Suppresses Tumor Growth. Mol Cancer Ther 2010; 9(2): 379–88
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  • Publication
    Dalantercept
    Jan 1, 2010
    Genetic and pharmacological targeting of activin receptor-like kinase 1 impairs tumor growth and angiogenesis. J Exp Med 2010; 207(1): 85-100
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  • Publication
    Sotatercept
    Jan 1, 2010
    Treatment with a soluble receptor for activin improves bone mass and structure in the axial and appendicular skeleton of female cynomolgus macaques (Macaca fascicularis). Bone 2010;46(1):64-71
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