ACE-041 (Advanced Cancer)

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ACE-041 is a protein therapeutic that binds a member of the GDF family necessary for angiogenesis. In preclinical models, systemic administration of ACE-041 inhibits VEGF and FGF-induced angiogenesis.

The ability of ACE-041 to simultaneously inhibit multiple angiogenic factors is expected to provide significant benefit to patients suffering from hematologic and solid tumors.